Cholera remains a major global public health challenge, with an estimated 1.3 to 4 million cases and tens of thousands of deaths reported worldwide each year. Caused by the bacterium Vibrio cholerae, ...

Cholera bacteria use hair-like appendages called pili to attach to surfaces. In this image, the pili are labeled with a fluorescent green dye. (Image credit: Fitnat Yildiz and Kyle Floyd) ...

Working with Vibrio cholerae, the bacterium that causes the severe diarrheal disease of cholera, microbiologists at the University at Buffalo have revealed new information on a cellular signaling ...

A toxin secreted by cholera bacteria can inhibit the growth of colorectal cancer without causing any measurable damage to the body. This is shown by a new study by researchers at Umeå University ...

Proteins usually undergo modifications during or after their synthesis in the endoplasmic reticulum (ER) and Golgi apparatus network inside eukaryotic cells. One such modification is glycosylation, ...

Scientists have now discovered and characterised the structure and function of a so far unknown Vibrio toxin. A team used the worm Caenorhabditis elegans as a predatory host for the bacteria and ...

Although oral cholera vaccines exist, the recent spike in cases and limited production capacity have outpaced the global vaccine supply, prompting researchers to explore alternative protection ...

Diarrheal disease constitutes one of the major causes of morbidity and mortality in infants and young children on a global scale (1). We know from clinical and laboratory studies that certain ...

Free-swimming cholera bacteria are much less infectious than bacteria in biofilms, aggregates of bacterial cells embedded in a sticky matrix that form on surfaces. This accounts for the surprising ...