I studied cryo-EM (cryo-electron microscopy) since my grad school time at Baylor College of Medicine, which was in 1996. I’ve been working with electron microscopy ever since. We're interested in cryo ...

A team of researchers has developed a theoretical model to design a soft material that demonstrates autonomous oscillating properties that mimic biological functions, like heartbeat. Northwestern ...

HSP90 chaperone undergoes dynamic cycling process: HSP90 transits between open and closed states to promote maturation of polypeptide clients into functional proteins with the help of ATP and a ...

Researchers have discovered how unstructured segments of surface proteins regulate the biological function of a cell. Their study, published in Nature Communications, sheds new light on the interplay ...

There is clear evidence for the rejuvenation of specific biological functions is now available in model organisms for a growing range of treatments. Achieving full medical control of aging, however, ...

A new synthetic biology toolkit developed at Northwestern University will help researchers design mammalian cells with new functionalities. The toolkit, called the Composable Mammalian Elements of ...

The triphosphate tunnel metalloenzyme (TTM) superfamily comprises a group of enzymes that hydrolyze organophosphate substrates. They exist in all domains of life, yet the biological role of most ...

New understanding of circadian rhythms could be key to stronger, drought-resistant crops in the face of climate change. The biological clock of a popular food crop controls close to three-quarters of ...

Northwestern Engineering researchers have developed a theoretical model to design soft materials that demonstrate autonomous oscillating properties that mimic biological functions. The work could ...