Genes in living cells are activated - or not - by proteins called transcription factors. The mechanisms by which these proteins activate certain genes and deactivate others play a fundamental role in ...

I studied cryo-EM (cryo-electron microscopy) since my grad school time at Baylor College of Medicine, which was in 1996. I’ve been working with electron microscopy ever since. We're interested in cryo ...

Researchers have discovered how unstructured segments of surface proteins regulate the biological function of a cell. Their study, published in Nature Communications, sheds new light on the interplay ...

A team of researchers has developed a theoretical model to design a soft material that demonstrates autonomous oscillating properties that mimic biological functions, like heartbeat. Northwestern ...

HSP90 chaperone undergoes dynamic cycling process: HSP90 transits between open and closed states to promote maturation of polypeptide clients into functional proteins with the help of ATP and a ...

Researchers have created functional brain-like tissue without relying on any animal-derived materials, marking a major step toward more ethical and reproducible neurological research.

There is clear evidence for the rejuvenation of specific biological functions is now available in model organisms for a growing range of treatments. Achieving full medical control of aging, however, ...

In most cases, this manifested as reduced DNA methylation activity. As this process plays a key role in a number of ...

Research will focus on the genome-wide identification of microexons to advance the knowledge on gene functions.