Whole-mount immunolabeling enabled high-resolution visualization of peripheral nerve infiltration patterns within melanoma, ...

The ß-ARs play an important role in CV health and disease and are mainstay targets of ß blockers in the treatment of hypertension, congestive HF, and coronary disease. Both genetic association and ...

Nerve fibers within melanomas can slow their growth, according to a study led by Weill Cornell Medicine investigators. The ...

However, a new study has identified a surprising “brake.” Investigating melanoma in mouse models, the team discovered that sympathetic nerves, the same ones responsible for the “fight-or-flight” ...

Background Sympathetic signalling plays a critical role in the initiation and progression of various malignancies. However, ...

Recent clinical studies have suggested that phenylacetylglutamine (PAGln), a novel gut microbial metabolite, can mechanistically modulate patients' risk of developing cardiovascular disease (CVD) and ...